李昕阳

出生年月：1990-01

民 族：汉

职 称：副教授

学科专业：真菌天然产物化学与合成生物学

邮 箱：xinyangli@scuec.edu.cn

教育经历

2015.09-2019.06：浙江大学，医学博士

2012.09-2015.06：南京中医药大学，医学硕士

2008.09-2012.06：陕西中医药大学，医学学士

工作经历

2023.07至今：中南民族大学药学院，副教授，硕士研究生导师

2019.09-2022.03，东京大学，博士后，合作导师：Ikuro Abe教授

主要荣誉

湖北省“楚天学者”人才计划

主要研究方向

1.真菌天然产物生物合成途径解析及酶学机制研究

2.基于基因组挖掘手段的天然产物发现及其生物合成研究

科研项目

1.国家自然科学基金青年项目（22307148），2024.01-2026.12，30万元，主持

2.中央高校科研业务基金（CZQ24022），2024.05-2026.05，18万元，主持

代表性研究成果

1.Gao-Ke Peng, Facheng Su, Ji-Kai Liu,He-Ping Chen*,Xinyang Li*.Drimane Sesquiterpenes Isolated from the Fruiting Body of theClavarioid FungusRamaria botrytoides.Molecules.2026, 31, 645.

2.Li-Li Guo^#, Yu Wang^#,Xinyang Li^#,*,He-Ping Chen*, Ji-Kai Liu*.Bergamotane-family sesquiterpenes from histone deacetylase inhibitor modified cultures of the fungicolous fungusMontagnula donacina(Niessl) Wanas., E.B.G. Jones & K.D. Hyde.Phytochemistry.2025, 240, 114630.

3.Xinyang Li, Jinzhong Xu*,Pinmei Wang, Wanjing Ding. Novel Indole Diketopiperazine Stereoisomers from a Marine-Derived FungusAspergillussp.Mycology.2023, 14, 1-10.

4.Xinyang Li^†, He-Ping Chen^†, Lin Zhou^†, Jing Fan, Takayoshi Awakawa, Takahiro Mori, Richiro Ushimaru*, Ikuro Abe*, Ji-Kai Liu*. Cordycicadins A-D, Antifeedant Polyketides from the Entomopathogenic FungusCordyceps cicadaeJXCH1.Org. Lett.2022, 24, 8627-8632.

5.Qing-Yuan Wang^†, He-Ping Chen^†, Kai-Yue Wu,Xinyang Li*, Ji-Kai Liu*. Antibacterial and β-Site amyloid precursor protein cleaving enzyme 1 inhibitory polyketides from the fungusAspergillus chevalieri.Front. Microbiol.2022,13, 1051281.

6.Lin Zhou^†,He-Ping Chen^†,Xinyang Li*, Ji-Kai Liu*.Ganoaustralins A and B, Unusual Aromatic Triterpenes from the MushroomGanoderma australe.Pharmaceuticals.2022, 15,1520.

7.Xinyang Li^†, Takayoshi Awakawa^†, Takahiro Mori, Meiqi Ling,Bin Wu, Ikuro Abe*. Heterodimeric Non-heme Iron Enzymes in Fungal Meroterpenoid Biosynthesis.J. Am. Chem. Soc.2021,143, 21425-21432.

8.Xinyang Li, Jian-ming Lv, Dan Hu, Ikuro Abe*. Biosynthesis of Alkyne-containing Natural Products.RSC Chem. Biol.2021,2, 166-180.

9.Suoyu Cen, Jia Jia, Yichao Ge, Yihan Ma,Xinyang Li, Jihua Wei, Yuefan Bai, Xiaodan Wu, Jianfeng Song, Hongkai Bi, Bin Wu*. A New Antibacterial 3,5-dimethylorsellinic Acid-based Meroterpene from the Marine FungusAspergillussp. CSYZ-1.Fitoterapia,2021, 152, 104908.

10.Jinyan Jiang,Xinyang Li,Takahiro Mori,Takayoshi Awakawa*,Ikuro Abe*.Novel Cyclohexyl Meroterpenes Produced by Combinatorial Biosynthesis.Chem. Pharm. Bull.,2021, 69, 444-446.

11.Xinyang Li, Wanjing Ding, Pinmei Wang, Jinzhong Xu*.Two Novel Aspochalasins from the Gut FungusAspergillussp. Z4.Mar. Drugs,2018, 16, 343.

12.Xinyang Li, Zhanhai Zhao, Wanjing Ding, Bin Ye, Pinmei Wang, Jinzhong Xu*. Aspochalazine A, a Novel Polycyclic Aspochalasin from the FungusAspergillussp. Z4.Tetrahedron Lett,2017, 58, 2405-2408.

(^†Co-first author; *Corresponding author)